In upper Sindh, this is the most important town. More than 2000 years ago the town was at Armor, nine kms (6 miles) east of the present site, but was relocated in 962 A.D., when owing to an earthquake, the Indus diverted its course to its present channel. By the 13th century the twin towns of Sukkur and Rohri were bustling river ports that reached their zenith in the 17th century.

Worth visiting here is the Minaret of Masum Shah. This light house shaped brick minaret was built by Mir Muhammad Masum, a local soldier appointed Nawab of Sukkur by the Emperor Akbar. The tower is slightly tilted and is 84 ft. in height, 84 ft. in circumference with an equivalent number of steps leading up to its top. Masum Shah is buried, along with other family members, in a pavilion near the minaret.